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The regulation of M(1) muscarinic acetylcholine receptor desensitization by synaptic activity in cultured hippocampal neurons

To better understand metabotropic/ionotropic integration in neurons we have examined the regulation of M(1) muscarinic acetylcholine (mACh) receptor signalling in mature (> 14 days in vitro), synaptically-active hippocampal neurons in culture. Using a protocol where neurons are exposed to an EC(5...

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Detalles Bibliográficos
Autores principales: Willets, Jonathon M, Nelson, Carl P, Nahorski, Stefan R, Challiss, R A John
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658029/
https://www.ncbi.nlm.nih.gov/pubmed/17908240
http://dx.doi.org/10.1111/j.1471-4159.2007.04931.x