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Integrating BRAF/MEK inhibitors into combination therapy for melanoma
The discovery of BRAF mutations in melanoma has not yet translated into clinical success, suggesting that BRAF/MEK inhibitors will need to be combined with other agents. In the current review, we discuss other pathways likely to be important for melanoma progression and suggest possible drug combina...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658537/ https://www.ncbi.nlm.nih.gov/pubmed/19156138 http://dx.doi.org/10.1038/sj.bjc.6604891 |