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Frequent overexpression of HMGA1 and 2 in gastroenteropancreatic neuroendocrine tumours and its relationship to let-7 downregulation

The molecular pathogenesis of gastroenteropancreatic (GEP) neuroendocrine tumours (NETs) remains to be elucidated. High-mobility group A (HMGA) proteins play important roles in the regulation of transcription, differentiation, and neoplastic transformation. In this study, the expression of HMGA1 and...

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Detalles Bibliográficos
Autores principales: Rahman, M M, Qian, Z R, Wang, E L, Sultana, R, Kudo, E, Nakasono, M, Hayashi, T, Kakiuchi, S, Sano, T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658538/
https://www.ncbi.nlm.nih.gov/pubmed/19156147
http://dx.doi.org/10.1038/sj.bjc.6604883