Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly-made proteins with complex topologies

Folding within the crowded cellular milieu often requires assistance from molecular chaperones that prevent inappropriate interactions leading to aggregation and toxicity. The contribution of individual chaperones to folding the proteome remains elusive. We here demonstrate that the eukaryotic chape...

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Detalles Bibliográficos
Autores principales: Yam, Alice Y., Xia, Yu, Jill Lin, Hen-Tzu, Burlingame, Alma, Gerstein, Mark, Frydman, Judith
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658641/
https://www.ncbi.nlm.nih.gov/pubmed/19011634
http://dx.doi.org/10.1038/nsmb.1515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658641/
https://www.ncbi.nlm.nih.gov/pubmed/19011634
http://dx.doi.org/10.1038/nsmb.1515

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