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Metabolite profiling studies in Saccharomyces cerevisiae: an assisting tool to prioritize host targets for antiviral drug screening

BACKGROUND: The cellular proteins Pat1p, Lsm1p, and Dhh1p are required for the replication of some positive-strand viruses and therefore are potential targets for new antiviral drugs. To prioritize host targets for antiviral drug screening a comparative metabolome analysis in Saccharomyces cerevisia...

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Detalles Bibliográficos
Autores principales: Schneider, Konstantin, Krömer, Jens Olaf, Wittmann, Christoph, Alves-Rodrigues, Isabel, Meyerhans, Andreas, Diez, Juana, Heinzle, Elmar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658664/
https://www.ncbi.nlm.nih.gov/pubmed/19183481
http://dx.doi.org/10.1186/1475-2859-8-12