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Evaluation of a microarray-hybridization based method applicable for discovery of single nucleotide polymorphisms (SNPs) in the Pseudomonas aeruginosa genome

BACKGROUND: Whole genome sequencing techniques have added a new dimension to studies on bacterial adaptation, evolution and diversity in chronic infections. By using this powerful approach it was demonstrated that Pseudomonas aeruginosa undergoes intense genetic adaptation processes, crucial in the...

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Detalles Bibliográficos
Autores principales: Dötsch, Andreas, Pommerenke, Claudia, Bredenbruch, Florian, Geffers, Robert, Häussler, Susanne
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658670/
https://www.ncbi.nlm.nih.gov/pubmed/19152677
http://dx.doi.org/10.1186/1471-2164-10-29