Distinct Roles for FOXP3(+) and FOXP3(−) CD4(+) T Cells in Regulating Cellular Immunity to Uncomplicated and Severe Plasmodium falciparum Malaria

Failure to establish an appropriate balance between pro- and anti-inflammatory immune responses is believed to contribute to pathogenesis of severe malaria. To determine whether this balance is maintained by classical regulatory T cells (CD4(+) FOXP3(+) CD127(−/low); Tregs) we compared cellular resp...

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Detalles Bibliográficos
Autores principales: Walther, Michael, Jeffries, David, Finney, Olivia C., Njie, Madi, Ebonyi, Augustine, Deininger, Susanne, Lawrence, Emma, Ngwa-Amambua, Alfred, Jayasooriya, Shamanthi, Cheeseman, Ian H., Gomez-Escobar, Natalia, Okebe, Joseph, Conway, David J., Riley, Eleanor M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658808/
https://www.ncbi.nlm.nih.gov/pubmed/19343213
http://dx.doi.org/10.1371/journal.ppat.1000364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658808/
https://www.ncbi.nlm.nih.gov/pubmed/19343213
http://dx.doi.org/10.1371/journal.ppat.1000364

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