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IP-10-Mediated T Cell Homing Promotes Cerebral Inflammation over Splenic Immunity to Malaria Infection

Plasmodium falciparum malaria causes 660 million clinical cases with over 2 million deaths each year. Acquired host immunity limits the clinical impact of malaria infection and provides protection against parasite replication. Experimental evidence indicates that cell-mediated immune responses also...

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Detalles Bibliográficos
Autores principales: Nie, Catherine Q., Bernard, Nicholas J., Norman, M. Ursula, Amante, Fiona H., Lundie, Rachel J., Crabb, Brendan S., Heath, William R., Engwerda, Christian R., Hickey, Michael J., Schofield, Louis, Hansen, Diana S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658824/
https://www.ncbi.nlm.nih.gov/pubmed/19343215
http://dx.doi.org/10.1371/journal.ppat.1000369