PKC and PKA Phosphorylation Affect the Subcellular Localization of Claudin-1 in Melanoma Cells

Cytoplasmic expression of claudin-1 in metastatic melanoma cells correlates to increased migration, and increased secretion of MMP-2 in a PKC dependent manner, whereas claudin-1 nuclear expression is found in benign nevi. Melanoma cells were transfected with a vector expressing CLDN-1 fused to a nuc...

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Detalles Bibliográficos
Autores principales: French, Amanda D., Fiori, Jennifer L., Camilli, Tura C., Leotlela, Poloko D., O'Connell, Michael P., Frank, Brittany P., Subaran, Sarah, Indig, Fred. E., Taub, Dennis D., Weeraratna, Ashani T.
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2009
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658888/
https://www.ncbi.nlm.nih.gov/pubmed/19305641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658888/
https://www.ncbi.nlm.nih.gov/pubmed/19305641

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