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Structure of the DBL3x domain of pregnancy-associated malaria protein VAR2CSA complexed with chondroitin sulfate A

Plasmodium falciparum–infected erythrocytes bind to chondroitin sulfate A (CSA) in the placenta via the VAR2CSA protein, a member of the P. falciparum erythrocyte membrane protein-1 family, leading to life-threatening malaria in pregnant women with severe effects on their fetuses and newborns. Here...

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Detalles Bibliográficos
Autores principales: Singh, Kavita, Gittis, Apostolos G, Nguyen, Phuc, Gowda, D Channe, Miller, Louis H, Garboczi, David N
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658892/
https://www.ncbi.nlm.nih.gov/pubmed/19172746