Peripheral blood monocytes are responsible for γδ T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP

Nitrogen-containing bisphosphonates indirectly activate Vγ9Vδ2 T cells through inhibition of farnesyl pyrophosphate synthase and intracellular accumulation of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), but the cells responsible for Vγ9Vδ2 T cell activation through IPP/DMAPP...

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Detalles Bibliográficos
Autores principales: Roelofs, Anke J, Jauhiainen, Marjo, Mönkkönen, Hannu, Rogers, Michael J, Mönkkönen, Jukka, Thompson, Keith
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659391/
https://www.ncbi.nlm.nih.gov/pubmed/19016713
http://dx.doi.org/10.1111/j.1365-2141.2008.07435.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659391/
https://www.ncbi.nlm.nih.gov/pubmed/19016713
http://dx.doi.org/10.1111/j.1365-2141.2008.07435.x

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