A New Splice Variant of the Mouse SIRT3 Gene Encodes the Mitochondrial Precursor Protein

BACKGROUND: Mammals have seven NAD-dependent protein deacetylases. These proteins, called sirtuins, are homologous to yeast Sir2, and are emerging as important regulators of lifespan and intermediary metabolism. Three mammalian sirtuins, SIRT3-5 are mitochondrial. Sirtuins are highly conserved betwe...

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Detalles Bibliográficos
Autores principales: Cooper, Helen M., Huang, Jing-Yi, Verdin, Eric, Spelbrink, Johannes N.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659428/
https://www.ncbi.nlm.nih.gov/pubmed/19333382
http://dx.doi.org/10.1371/journal.pone.0004986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659428/
https://www.ncbi.nlm.nih.gov/pubmed/19333382
http://dx.doi.org/10.1371/journal.pone.0004986

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