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A New Splice Variant of the Mouse SIRT3 Gene Encodes the Mitochondrial Precursor Protein
BACKGROUND: Mammals have seven NAD-dependent protein deacetylases. These proteins, called sirtuins, are homologous to yeast Sir2, and are emerging as important regulators of lifespan and intermediary metabolism. Three mammalian sirtuins, SIRT3-5 are mitochondrial. Sirtuins are highly conserved betwe...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659428/ https://www.ncbi.nlm.nih.gov/pubmed/19333382 http://dx.doi.org/10.1371/journal.pone.0004986 |