Cargando…
A High-Speed Congenic Strategy Using First-Wave Male Germ Cells
BACKGROUND: In laboratory mice and rats, congenic breeding is essential for analyzing the genes of interest on specific genetic backgrounds and for analyzing quantitative trait loci. However, in theory it takes about 3–4 years to achieve a strain carrying about 99% of the recipient genome at the ten...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659429/ https://www.ncbi.nlm.nih.gov/pubmed/19333383 http://dx.doi.org/10.1371/journal.pone.0004943 |