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A High-Speed Congenic Strategy Using First-Wave Male Germ Cells

BACKGROUND: In laboratory mice and rats, congenic breeding is essential for analyzing the genes of interest on specific genetic backgrounds and for analyzing quantitative trait loci. However, in theory it takes about 3–4 years to achieve a strain carrying about 99% of the recipient genome at the ten...

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Detalles Bibliográficos
Autores principales:	Ogonuki, Narumi, Inoue, Kimiko, Hirose, Michiko, Miura, Ikuo, Mochida, Keiji, Sato, Takahiro, Mise, Nathan, Mekada, Kazuyuki, Yoshiki, Atsushi, Abe, Kuniya, Kurihara, Hiroki, Wakana, Shigeharu, Ogura, Atsuo
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659429/ https://www.ncbi.nlm.nih.gov/pubmed/19333383 http://dx.doi.org/10.1371/journal.pone.0004943

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