Development of a Novel Virtual Screening Cascade Protocol to Identify Potential Trypanothione Reductase Inhibitors

[Image: see text] The implementation of a novel sequential computational approach that can be used effectively for virtual screening and identification of prospective ligands that bind to trypanothione reductase (TryR) is reported. The multistep strategy combines a ligand-based virtual screening for...

Descripción completa

Detalles Bibliográficos
Autores principales: Perez-Pineiro, Rolando, Burgos, Asdrubal, Jones, Deuan C., Andrew, Lena C., Rodriguez, Hortensia, Suarez, Margarita, Fairlamb, Alan H., Wishart, David S.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659691/
https://www.ncbi.nlm.nih.gov/pubmed/19296695
http://dx.doi.org/10.1021/jm801306g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659691/
https://www.ncbi.nlm.nih.gov/pubmed/19296695
http://dx.doi.org/10.1021/jm801306g

Ejemplares similares