Cargando…

Functional Interactions between KCNE1 C-Terminus and the KCNQ1 Channel

The KCNE1 gene product (minK protein) associates with the cardiac KvLQT1 potassium channel (encoded by KCNQ1) to create the cardiac slowly activating delayed rectifier, I(Ks). Mutations throughout both genes are linked to the hereditary cardiac arrhythmias in the Long QT Syndrome (LQTS). KCNE1 exert...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Jerri, Zheng, Renjian, Melman, Yonathan F., McDonald, Thomas V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659744/
https://www.ncbi.nlm.nih.gov/pubmed/19340287
http://dx.doi.org/10.1371/journal.pone.0005143