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Interaction between CXCR4 and CCL20 Pathways Regulates Tumor Growth

The chemokine receptor CXCR4 and its ligand CXCL12 is overexpressed in the majority of tumors and is critically involved in the development and metastasis of these tumors. CXCR4 is expressed in malignant tumor cells whereas its ligand SDF-1 (CXCL12) is expressed mainly by cancer associated fibroblas...

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Detalles Bibliográficos
Autores principales: Beider, Katia, Abraham, Michal, Begin, Michal, Wald, Hanna, Weiss, Ido D., Wald, Ori, Pikarsky, Eli, Abramovitch, Rinat, Zeira, Evelyne, Galun, Eithan, Nagler, Arnon, Peled, Amnon
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659745/
https://www.ncbi.nlm.nih.gov/pubmed/19340288
http://dx.doi.org/10.1371/journal.pone.0005125