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Paracrine Diffusion of PrP(C) and Propagation of Prion Infectivity by Plasma Membrane-Derived Microvesicles

Cellular prion protein (PrP(c)) is a physiological constituent of eukaryotic cells. The cellular pathways underlying prions spread from the sites of prions infection/peripheral replication to the central nervous system are still not elucidated. Membrane-derived microvesicles (MVs) are submicron (0.1...

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Detalles Bibliográficos
Autores principales: Mattei, Vincenzo, Barenco, Maria Grazia, Tasciotti, Vincenzo, Garofalo, Tina, Longo, Agostina, Boller, Klaus, Löwer, Johannes, Misasi, Roberta, Montrasio, Fabio, Sorice, Maurizio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659799/
https://www.ncbi.nlm.nih.gov/pubmed/19337375
http://dx.doi.org/10.1371/journal.pone.0005057