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Paracrine Diffusion of PrP(C) and Propagation of Prion Infectivity by Plasma Membrane-Derived Microvesicles
Cellular prion protein (PrP(c)) is a physiological constituent of eukaryotic cells. The cellular pathways underlying prions spread from the sites of prions infection/peripheral replication to the central nervous system are still not elucidated. Membrane-derived microvesicles (MVs) are submicron (0.1...
Autores principales: | Mattei, Vincenzo, Barenco, Maria Grazia, Tasciotti, Vincenzo, Garofalo, Tina, Longo, Agostina, Boller, Klaus, Löwer, Johannes, Misasi, Roberta, Montrasio, Fabio, Sorice, Maurizio |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659799/ https://www.ncbi.nlm.nih.gov/pubmed/19337375 http://dx.doi.org/10.1371/journal.pone.0005057 |
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