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On the possibility of using polycrystalline material in the development of structure-based generic assays

The discovery of ligands that bind specifically to a targeted protein benefits from the development of generic assays for high-throughput screening of a library of chemicals. Protein powder diffraction (PPD) has been proposed as a potential method for use as a structure-based assay for high-throughp...

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Detalles Bibliográficos
Autores principales: Allaire, Marc, Moiseeva, Natalia, Botez, Cristian E., Engel, Matthew A., Stephens, Peter W.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659885/
https://www.ncbi.nlm.nih.gov/pubmed/19307720
http://dx.doi.org/10.1107/S090744490900256X