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Probing the Flexibility of Large Conformational Changes in Protein Structures through Local Perturbations
Protein conformational changes and dynamic behavior are fundamental for such processes as catalysis, regulation, and substrate recognition. Although protein dynamics have been successfully explored in computer simulation, there is an intermediate-scale of motions that has proven difficult to simulat...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660149/ https://www.ncbi.nlm.nih.gov/pubmed/19343225 http://dx.doi.org/10.1371/journal.pcbi.1000343 |