Studies on the binding affinity of anticancer drug mitoxantrone to chromatin, DNA and histone proteins

Mitoxantrone is a potent antitumor drug, widely used in the treatment of various cancers. In the present study, we have investigated and compared the affinity of anticancer drug, mitoxantrone, to EDTA-soluble chromatin (SE-chromatin), DNA and histones employing UV/Vis, fluorescence, CD spectroscopy,...

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Detalles Bibliográficos
Autores principales: Hajihassan, Zahra, Rabbani-Chadegani, Azra
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660295/
https://www.ncbi.nlm.nih.gov/pubmed/19284573
http://dx.doi.org/10.1186/1423-0127-16-31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660295/
https://www.ncbi.nlm.nih.gov/pubmed/19284573
http://dx.doi.org/10.1186/1423-0127-16-31

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