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Ciliary neurotrophic factor (CNTF) plus soluble CNTF receptor α increases cyclooxygenase-2 expression, PGE(2 )release and interferon-γ-induced CD40 in murine microglia

BACKGROUND: Ciliary neurotrophic factor (CNTF) has been regarded as a potent trophic factor for motor neurons. However, recent studies have shown that CNTF exerts effects on glial cells as well as neurons. For instance, CNTF stimulates astrocytes to secrete FGF-2 and rat microglia to secrete glial c...

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Detalles Bibliográficos
Autores principales: Lin, Hsiao-Wen, Jain, Mohit Raja, Li, Hong, Levison, Steven W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660310/
https://www.ncbi.nlm.nih.gov/pubmed/19267906
http://dx.doi.org/10.1186/1742-2094-6-7