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Matrix metalloproteinase-7 facilitates immune access to the CNS in experimental autoimmune encephalomyelitis

BACKGROUND: Metalloproteinase inhibitors can protect mice against experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis (MS). Matrix metalloproteinase-9 (MMP-9) has been implicated, but it is not clear if other MMPs are also involved, including matrilysin/MMP-7 – an...

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Detalles Bibliográficos
Autores principales: Buhler, Lillian A, Samara, Ramsey, Guzman, Esther, Wilson, Carole L, Krizanac-Bengez, Liljana, Janigro, Damir, Ethell, Douglas W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660336/
https://www.ncbi.nlm.nih.gov/pubmed/19267908
http://dx.doi.org/10.1186/1471-2202-10-17