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HCV Tumor Promoting Effect Is Dependent on Host Genetic Background

BACKGROUND: The hepatitis C virus (HCV) is one of the major risk factors for the development of hepatocellular carcinoma (HCC). Nevertheless, transgenic mice which express the whole HCV polyprotein (HCV-Tg) do not develop HCC. Whereas chronic HCV infection causes inflammation in patients, in HCV-Tg...

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Detalles Bibliográficos
Autores principales: Klopstock, Naama, Katzenellenbogen, Mark, Pappo, Orit, Sklair-Levy, Miriam, Olam, Devorah, Mizrahi, Lina, Potikha, Tamara, Galun, Eithan, Goldenberg, Daniel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660413/
https://www.ncbi.nlm.nih.gov/pubmed/19340302
http://dx.doi.org/10.1371/journal.pone.0005025