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INK4/ARF Transcript Expression Is Associated with Chromosome 9p21 Variants Linked to Atherosclerosis

BACKGROUND: Genome-wide association studies (GWAS) have linked common single nucleotide polymorphisms (SNPs) on chromosome 9p21 near the INK4/ARF (CDKN2A/B) tumor suppressor locus with risk of atherosclerotic diseases and type 2 diabetes mellitus. To explore the mechanism of this association, we inv...

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Detalles Bibliográficos
Autores principales: Liu, Yan, Sanoff, Hanna K., Cho, Hyunsoon, Burd, Christin E., Torrice, Chad, Mohlke, Karen L., Ibrahim, Joseph G., Thomas, Nancy E., Sharpless, Norman E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660422/
https://www.ncbi.nlm.nih.gov/pubmed/19343170
http://dx.doi.org/10.1371/journal.pone.0005027