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NF-κB Mediates Tumor Necrosis Factor α-Induced Expression of Optineurin, a Negative Regulator of NF-κB

Optineurin is a ubiquitously expressed multifunctional cytoplasmic protein encoded by OPTN gene. The expression of optineurin is induced by various cytokines. Here we have investigated the molecular mechanisms which regulate optineurin gene expression and the relationship between optineurin and nucl...

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Detalles Bibliográficos
Autores principales: Sudhakar, Cherukuri, Nagabhushana, Ananthamurthy, Jain, Nishant, Swarup, Ghanshyam
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660438/
https://www.ncbi.nlm.nih.gov/pubmed/19340308
http://dx.doi.org/10.1371/journal.pone.0005114