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A Regulated Response to Impaired Respiration Slows Behavioral Rates and Increases Lifespan in Caenorhabditis elegans

When mitochondrial respiration or ubiquinone production is inhibited in Caenorhabditis elegans, behavioral rates are slowed and lifespan is extended. Here, we show that these perturbations increase the expression of cell-protective and metabolic genes and the abundance of mitochondrial DNA. This res...

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Detalles Bibliográficos
Autores principales: Cristina, David, Cary, Michael, Lunceford, Adam, Clarke, Catherine, Kenyon, Cynthia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660839/
https://www.ncbi.nlm.nih.gov/pubmed/19360127
http://dx.doi.org/10.1371/journal.pgen.1000450