GM-CSF and IL-4 synergistically trigger dendritic cells to acquire retinoic acid-producing capacity

Retinoic acid (RA) produced by intestinal dendritic cells (DCs) imprints gut-homing specificity on lymphocytes and enhances Foxp3(+) regulatory T-cell differentiation. The expression of aldehyde dehydrogenase (ALDH) 1A in these DCs is essential for the RA production. However, it remains unclear how...

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Detalles Bibliográficos
Autores principales: Yokota, Aya, Takeuchi, Hajime, Maeda, Naoko, Ohoka, Yoshiharu, Kato, Chieko, Song, Si-Young, Iwata, Makoto
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660862/
https://www.ncbi.nlm.nih.gov/pubmed/19190084
http://dx.doi.org/10.1093/intimm/dxp003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660862/
https://www.ncbi.nlm.nih.gov/pubmed/19190084
http://dx.doi.org/10.1093/intimm/dxp003

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