Chemical tools selectively target components of the PKA system

BACKGROUND: In the eukaryotic cell the cAMP-dependent protein kinase (PKA) is a key enzyme in signal transduction and represents the main target of the second messenger cAMP. Here we describe the design, synthesis and characterisation of specifically tailored cAMP analogs which can be utilised as a...

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Detalles Bibliográficos
Autores principales: Bertinetti, Daniela, Schweinsberg, Sonja, Hanke, Susanne E, Schwede, Frank, Bertinetti, Oliver, Drewianka, Stephan, Genieser, Hans-Gottfried, Herberg, Friedrich W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660902/
https://www.ncbi.nlm.nih.gov/pubmed/19216744
http://dx.doi.org/10.1186/1472-6769-9-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660902/
https://www.ncbi.nlm.nih.gov/pubmed/19216744
http://dx.doi.org/10.1186/1472-6769-9-3

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