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Chemical tools selectively target components of the PKA system
BACKGROUND: In the eukaryotic cell the cAMP-dependent protein kinase (PKA) is a key enzyme in signal transduction and represents the main target of the second messenger cAMP. Here we describe the design, synthesis and characterisation of specifically tailored cAMP analogs which can be utilised as a...
Autores principales: | Bertinetti, Daniela, Schweinsberg, Sonja, Hanke, Susanne E, Schwede, Frank, Bertinetti, Oliver, Drewianka, Stephan, Genieser, Hans-Gottfried, Herberg, Friedrich W |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660902/ https://www.ncbi.nlm.nih.gov/pubmed/19216744 http://dx.doi.org/10.1186/1472-6769-9-3 |
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