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Non-homologous end joining in class switch recombination: the beginning of the end

Immunoglobulin class switch recombination (CSR) is initiated by a B-cell-specific factor, activation-induced deaminase, probably through deamination of deoxycytidine residues within the switch (S) regions. The initial lesions in the S regions are subsequently processed, resulting in the production o...

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Detalles Bibliográficos
Autores principales: Kotnis, Ashwin, Du, Likun, Liu, Chonghai, Popov, Sergey W., Pan-Hammarström, Qiang
Formato: Texto
Lenguaje:English
Publicado: The Royal Society 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660918/
https://www.ncbi.nlm.nih.gov/pubmed/19008195
http://dx.doi.org/10.1098/rstb.2008.0196