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The Mycobacterium tuberculosis Phagosome Is a HLA-I Processing Competent Organelle
Mycobacterium tuberculosis (Mtb) resides in a long-lived phagosomal compartment that resists maturation. The manner by which Mtb antigens are processed and presented on MHC Class I molecules is poorly understood. Using human dendritic cells and IFN-γ release by CD8(+) T cell clones, we examined the...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661020/ https://www.ncbi.nlm.nih.gov/pubmed/19360129 http://dx.doi.org/10.1371/journal.ppat.1000374 |