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The Mycobacterium tuberculosis Phagosome Is a HLA-I Processing Competent Organelle

Mycobacterium tuberculosis (Mtb) resides in a long-lived phagosomal compartment that resists maturation. The manner by which Mtb antigens are processed and presented on MHC Class I molecules is poorly understood. Using human dendritic cells and IFN-γ release by CD8(+) T cell clones, we examined the...

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Detalles Bibliográficos
Autores principales:	Grotzke, Jeff E., Harriff, Melanie J., Siler, Anne C., Nolt, Dawn, Delepine, Jacob, Lewinsohn, Deborah A., Lewinsohn, David M.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661020/ https://www.ncbi.nlm.nih.gov/pubmed/19360129 http://dx.doi.org/10.1371/journal.ppat.1000374

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