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N-Acetylcysteine Reverses Cocaine Induced Metaplasticity

Cocaine addiction is characterized by an impaired ability to develop adaptive behaviors that can compete with cocaine seeking, implying a deficit in the ability to induce plasticity in cortico-accumbens circuitry critical for regulating motivated behavior. RWe found that rats withdrawn from cocaine...

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Detalles Bibliográficos
Autores principales: Moussawi, Khaled, Pacchioni, Alejandra, Moran, Megan, Olive, M. Foster, Gass, Justin T., Lavin, Antonieta, Kalivas, Peter W
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661026/
https://www.ncbi.nlm.nih.gov/pubmed/19136971
http://dx.doi.org/10.1038/nn.2250