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Inverse Langmuir method for oligonucleotide microarray analysis

BACKGROUND: An algorithm for the analysis of Affymetrix Genechips is presented. This algorithm, referred to as the Inverse Langmuir Method (ILM), estimates the binding of transcripts to complementary probes using DNA/RNA hybridization free energies, and the hybridization between partially complement...

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Detalles Bibliográficos
Autores principales: Mulders, Geert CWM, Barkema, Gerard T, Carlon, Enrico
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661052/
https://www.ncbi.nlm.nih.gov/pubmed/19232092
http://dx.doi.org/10.1186/1471-2105-10-64