Gamma-linolenic acid inhibits both tumour cell cycle progression and angiogenesis in the orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin D1, pRb, p53 and p27 protein expression

BACKGROUND: Gamma-linolenic acid is a known inhibitor of tumour cell proliferation and migration in both in vitro and in vivo conditions. The aim of the present study was to determine the mechanisms by which gamma-linolenic acid (GLA) osmotic pump infusion alters glioma cell proliferation, and wheth...

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Detalles Bibliográficos
Autores principales: Miyake, Juliano Andreoli, Benadiba, Marcel, Colquhoun, Alison
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661078/
https://www.ncbi.nlm.nih.gov/pubmed/19292920
http://dx.doi.org/10.1186/1476-511X-8-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661078/
https://www.ncbi.nlm.nih.gov/pubmed/19292920
http://dx.doi.org/10.1186/1476-511X-8-8

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