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Ephrin-B3 reverse signaling through Grb4 and cytoskeletal regulators mediates axon pruning

Receptor-like roles for ephrin-B proteins are implicated to control axon pathfinding by repulsion, although it is largely unknown how the reverse signals are coupled to downstream intracellular molecules and induce cytoskeletal reorganization at the axon terminal. Here, we show ephrin-B3 (EB3) funct...

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Detalles Bibliográficos
Autores principales: Xu, Nan-Jie, Henkemeyer, Mark
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661084/
https://www.ncbi.nlm.nih.gov/pubmed/19182796
http://dx.doi.org/10.1038/nn.2254