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Mouse Cofactor of BRCA1 (Cobra1) Is Required for Early Embryogenesis

BACKGROUND: Negative elongation factor (NELF) is a four-subunit protein complex conserved from Drosophila to humans. In vitro biochemical and tissue culture-based studies have demonstrated an important role of NELF in controlling RNA polymerase II (Pol II) pausing in transcription. However, the phys...

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Detalles Bibliográficos
Autores principales: Amleh, Asma, Nair, Sreejith J., Sun, Jianlong, Sutherland, Ann, Hasty, Paul, Li, Rong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661135/
https://www.ncbi.nlm.nih.gov/pubmed/19340312
http://dx.doi.org/10.1371/journal.pone.0005034