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Polymorphisms in the WNK1 Gene Are Associated with Blood Pressure Variation and Urinary Potassium Excretion

WNK1 - a serine/threonine kinase involved in electrolyte homeostasis and blood pressure (BP) control - is an excellent candidate gene for essential hypertension (EH). We and others have previously reported association between WNK1 and BP variation. Using tag SNPs (tSNPs) that capture 100% of common...

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Detalles Bibliográficos
Autores principales: Newhouse, Stephen, Farrall, Martin, Wallace, Chris, Hoti, Mimoza, Burke, Beverley, Howard, Philip, Onipinla, Abiodun, Lee, Kate, Shaw-Hawkins, Sue, Dobson, Richard, Brown, Morris, Samani, Nilesh J., Dominiczak, Anna F., Connell, John M., Lathrop, G. Mark, Kooner, Jaspal, Chambers, John, Elliott, Paul, Clarke, Robert, Collins, Rory, Laan, Maris, Org, Elin, Juhanson, Peeter, Veldre, Gudrun, Viigimaa, Margus, Eyheramendy, Susana, Cappuccio, Francesco P., Ji, Chen, Iacone, Roberto, Strazzullo, Pasquale, Kumari, Meena, Marmot, Michael, Brunner, Eric, Caulfield, Mark, Munroe, Patricia B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661139/
https://www.ncbi.nlm.nih.gov/pubmed/19347040
http://dx.doi.org/10.1371/journal.pone.0005003