Cargando…

Immunization with Radiation-Attenuated Plasmodium berghei Sporozoites Induces Liver cCD8α(+)DC that Activate CD8(+)T Cells against Liver-Stage Malaria

Immunization with radiation (γ)-attenuated Plasmodia sporozoites (γ-spz) confers sterile and long-lasting immunity against malaria liver-stage infection. In the P. berghei γ-spz model, protection is linked to liver CD8(+) T cells that express an effector/memory (T(EM)) phenotype, (CD44(hi)CD45RB(lo)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jobe, Ousman, Donofrio, Gina, Sun, Guangping, Liepinsh, Dmitry, Schwenk, Robert, Krzych, Urszula
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661143/ https://www.ncbi.nlm.nih.gov/pubmed/19347042 http://dx.doi.org/10.1371/journal.pone.0005075

Ejemplares similares

Infectious Sporozoites of Plasmodium berghei Effectively Activate Liver CD8α(+) Dendritic Cells
por: Parmar, Rajesh, et al.
Publicado: (2018)

Identification of a Novel CD8 T Cell Epitope Derived from Plasmodium berghei Protective Liver-Stage Antigen
por: Pichugin, Alexander, et al.
Publicado: (2018)

Intravital Observation of Plasmodium berghei Sporozoite Infection of the Liver
por: Frevert, Ute, et al.
Publicado: (2005)

Phenotypic characterization of Plasmodium berghei responsive CD8+ T cells after immunization with live sporozoites under chloroquine cover
por: Brando, Clara, et al.
Publicado: (2014)

Immunization with genetically attenuated P52-deficient Plasmodium berghei sporozoites induces a long-lasting effector memory CD8(+ )T cell response in the liver
por: Douradinha, Bruno, et al.
Publicado: (2011)

Development of an In Vitro Assay and Demonstration of Plasmodium berghei Liver-Stage Inhibition by TRAP-Specific CD8(+) T Cells
por: Longley, Rhea J., et al.
Publicado: (2015)

Biosynthesis of Pb44, the protective antigen of sporozoites of Plasmodium berghei
Publicado: (1981)

Expression and Localization Profiles of Rhoptry Proteins in Plasmodium berghei Sporozoites
por: Tokunaga, Naohito, et al.
Publicado: (2019)

Memory CD8 T Cells Specific for Plasmodia Liver-Stage Antigens Maintain Protracted Protection Against Malaria
por: Krzych, Urszula, et al.
Publicado: (2012)

Serial Analysis of Gene Expression in Plasmodium berghei salivary gland sporozoites
por: Rosinski-Chupin, Isabelle, et al.
Publicado: (2007)

Cross-protection between attenuated Plasmodium berghei and P. yoelii sporozoites
por: SEDEGAH, M, et al.
Publicado: (2007)

Unique transcriptional profile of liver-resident memory CD8(+) T cells induced by immunization with malaria sporozoites
por: Tse, Sze-Wah, et al.
Publicado: (2013)

Varying Immunizations With Plasmodium Radiation-Attenuated Sporozoites Alter Tissue-Specific CD8(+) T Cell Dynamics
por: Frank, Roland, et al.
Publicado: (2018)

Long Term Protection after Immunization with P. berghei Sporozoites Correlates with Sustained IFNγ Responses of Hepatic CD8+ Memory T Cells
por: Nganou-Makamdop, Krystelle, et al.
Publicado: (2012)

Protective CD8+ T lymphocytes in Primates Immunized with Malaria Sporozoites
por: Weiss, Walter R., et al.
Publicado: (2012)

CSP—A Model for In Vivo Presentation of Plasmodium berghei Sporozoite Antigens by Hepatocytes
por: Balam, Saidou, et al.
Publicado: (2012)

A Plasmodium berghei sporozoite-based vaccination platform against human malaria
por: Mendes, António M., et al.
Publicado: (2018)

Addition of histamine to subcutaneously injected Plasmodium berghei sporozoites increases the parasite liver load and could facilitate whole-parasite vaccination
por: Pfeil, Johannes, et al.
Publicado: (2015)

Defining rules of CD8(+) T cell expansion against pre-erythrocytic Plasmodium antigens in sporozoite-immunized mice
por: Billman, Zachary P., et al.
Publicado: (2016)

Extreme CD8 T Cell Requirements for Anti-Malarial Liver-Stage Immunity following Immunization with Radiation Attenuated Sporozoites
por: Schmidt, Nathan W., et al.
Publicado: (2010)

Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria
por: Bijker, Else M, et al.
Publicado: (2015)

Single-cell RNA sequencing reveals developmental heterogeneity among Plasmodium berghei sporozoites
por: Ruberto, Anthony A., et al.
Publicado: (2021)

Kupffer Cells Survive Plasmodium berghei Sporozoite Exposure and Respond with a Rapid Cytokine Release
por: Tweedell, Rebecca E., et al.
Publicado: (2018)

Transcriptional heterogeneity and tightly regulated changes in gene expression during Plasmodium berghei sporozoite development
por: Bogale, Haikel N., et al.
Publicado: (2021)

Tissue signatures influence the activation of intrahepatic CD8(+) T cells against malaria sporozoites
por: Morrot, Alexandre, et al.
Publicado: (2014)

In vivo CD8+ T Cell Dynamics in the Liver of Plasmodium yoelii Immunized and Infected Mice
por: Cabrera, Mynthia, et al.
Publicado: (2013)

CD68 acts as a major gateway for malaria sporozoite liver infection
por: Cha, Sung-Jae, et al.
Publicado: (2015)

Overexpression of Plasmodium berghei ATG8 by Liver Forms Leads to Cumulative Defects in Organelle Dynamics and to Generation of Noninfectious Merozoites
por: Voss, Christiane, et al.
Publicado: (2016)

CD8(+) DC, but Not CD8(−)DC, Isolated from BCG-Infected Mice Reduces Pathological Reactions Induced by Mycobacterial Challenge Infection
por: Gao, Xiaoling, et al.
Publicado: (2010)

Lymph-Node Resident CD8α(+) Dendritic Cells Capture Antigens from Migratory Malaria Sporozoites and Induce CD8(+) T Cell Responses
por: Radtke, Andrea J., et al.
Publicado: (2015)

The Alveolin IMC1h Is Required for Normal Ookinete and Sporozoite Motility Behaviour and Host Colonisation in Plasmodium berghei
por: Volkmann, Katrin, et al.
Publicado: (2012)

Plasmodium berghei circumsporozoite protein encapsulated in oligomannose-coated liposomes confers protection against sporozoite infection in mice
por: Terkawi, Mohamad Alaa, et al.
Publicado: (2014)

Plasmodium berghei sporozoites in nonreplicative vacuole are eliminated by a PI3P‐mediated autophagy‐independent pathway
por: Bindschedler, Annina, et al.
Publicado: (2020)

Comparative transcriptomics of porcine liver-resident CD8α(dim), liver CD8α(high) and circulating blood CD8α(high) NK cells reveals an intermediate phenotype of liver CD8α(high) NK cells
por: Hermans, Leen, et al.
Publicado: (2023)

Attenuated plasmodium sporozoite expressing MAGE-A3 induces antigen-specific CD8+ T cell response against lung cancer in mice
por: Zhou, Dong, et al.
Publicado: (2019)

CD4(+) T Cells Modulate Expansion and Survival but Not Functional Properties of Effector and Memory CD8(+) T Cells Induced by Malaria Sporozoites
por: Overstreet, Michael G., et al.
Publicado: (2011)

Toxicological Evaluation and Protective Effects of Ethanolic Leaf Extract of Cassia spectabilis DC on Liver and Kidney Function of Plasmodium berghei-Infected Mice
por: Ekasari, Wiwied, et al.
Publicado: (2022)

Plasmodium berghei Cap93, a novel oocyst capsule-associated protein, plays a role in sporozoite development
por: Sasaki, Hanae, et al.
Publicado: (2017)

Plasmodium berghei Kinesin-5 Associates With the Spindle Apparatus During Cell Division and Is Important for Efficient Production of Infectious Sporozoites
por: Zeeshan, Mohammad, et al.
Publicado: (2020)

A genetically modified Plasmodium berghei parasite as a surrogate for whole-sporozoite vaccination against P. vivax malaria
por: Moita, Diana, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_jhodd9etjcg25fkms0g73fjso6