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Fascin-1 Promoter Activity Is Regulated by CREB and the Aryl Hydrocarbon Receptor in Human Carcinoma Cells

BACKGROUND: Fascin is an actin-bundling protein that is absent from most normal epithelia yet is upregulated in multiple forms of human carcinoma, where its expression correlates clinically with a poor prognosis. How fascin-1 transcription is activated in carcinoma cells is largely unknown, although...

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Detalles Bibliográficos
Autores principales: Hashimoto, Yosuke, Loftis, David W., Adams, Josephine C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661145/
https://www.ncbi.nlm.nih.gov/pubmed/19340314
http://dx.doi.org/10.1371/journal.pone.0005130