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Generic Algorithm to Predict the Speed of Translational Elongation: Implications for Protein Biogenesis

Synonymous codon usage and variations in the level of isoaccepting tRNAs exert a powerful selective force on translation fidelity. We have developed an algorithm to evaluate the relative rate of translation which allows large-scale comparisons of the non-uniform translation rate on the protein bioge...

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Detalles Bibliográficos
Autores principales: Zhang, Gong, Ignatova, Zoya
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661179/
https://www.ncbi.nlm.nih.gov/pubmed/19343177
http://dx.doi.org/10.1371/journal.pone.0005036