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Antigenic Fingerprinting of H5N1 Avian Influenza Using Convalescent Sera and Monoclonal Antibodies Reveals Potential Vaccine and Diagnostic Targets

BACKGROUND: Transmission of highly pathogenic avian H5N1 viruses from poultry to humans have raised fears of an impending influenza pandemic. Concerted efforts are underway to prepare effective vaccines and therapies including polyclonal or monoclonal antibodies against H5N1. Current efforts are ham...

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Detalles Bibliográficos
Autores principales: Khurana, Surender, Suguitan, Amorsolo L., Rivera, Yonaira, Simmons, Cameron P., Lanzavecchia, Antonio, Sallusto, Federica, Manischewitz, Jody, King, Lisa R., Subbarao, Kanta, Golding, Hana
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661249/
https://www.ncbi.nlm.nih.gov/pubmed/19381279
http://dx.doi.org/10.1371/journal.pmed.1000049