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Mesenchymal Stem Cell Transition to Tumor-Associated Fibroblasts Contributes to Fibrovascular Network Expansion and Tumor Progression

BACKGROUND: Tumor associated fibroblasts (TAF), are essential for tumor progression providing both a functional and structural supportive environment. TAF, known as activated fibroblasts, have an established biological impact on tumorigenesis as matrix synthesizing or matrix degrading cells, contrac...

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Detalles Bibliográficos
Autores principales: Spaeth, Erika L., Dembinski, Jennifer L., Sasser, A. Kate, Watson, Keri, Klopp, Ann, Hall, Brett, Andreeff, Michael, Marini, Frank
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661372/
https://www.ncbi.nlm.nih.gov/pubmed/19352430
http://dx.doi.org/10.1371/journal.pone.0004992