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TCF7L2 Regulates Late Events in Insulin Secretion From Pancreatic Islet β-Cells
OBJECTIVE: Polymorphisms in the human TCF7L2 gene are associated with reduced insulin secretion and an increased risk of type 2 diabetes. However, the mechanisms by which TCF7L2 affect insulin secretion are still unclear. We define the effects of TCF7L2 expression level on mature β-cell function and...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661588/ https://www.ncbi.nlm.nih.gov/pubmed/19168596 http://dx.doi.org/10.2337/db08-1187 |