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Adipose Overexpression of Desnutrin Promotes Fatty Acid Use and Attenuates Diet-Induced Obesity

OBJECTIVE: To investigate the role of desnutrin in adipose tissue triacylglycerol (TAG) and fatty acid metabolism. RESEARCH DESIGN AND METHODS: We generated transgenic mice overexpressing desnutrin (also called adipose triglyceride lipase [ATGL]) in adipocytes (aP2-desnutrin) and also performed aden...

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Detalles Bibliográficos
Autores principales: Ahmadian, Maryam, Duncan, Robin E., Varady, Krista A., Frasson, Danubia, Hellerstein, Marc K., Birkenfeld, Andreas L., Samuel, Varman T., Shulman, Gerald I., Wang, Yuhui, Kang, Chulho, Sul, Hei Sook
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661591/
https://www.ncbi.nlm.nih.gov/pubmed/19136649
http://dx.doi.org/10.2337/db08-1644