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Mice With Hyperghrelinemia Are Hyperphagic and Glucose Intolerant and Have Reduced Leptin Sensitivity

OBJECTIVE: Ghrelin is the only known peripheral hormone to increase ingestive behavior. However, its role in the physiological regulation of energy homeostasis is unclear because deletion of ghrelin or its receptor does not alter food intake or body weight in mice fed a normal chow diet. We hypothes...

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Detalles Bibliográficos
Autores principales: Bewick, Gavin A., Kent, Aysha, Campbell, Daniel, Patterson, Michael, Ghatei, Mohammed A., Bloom, Stephen R., Gardiner, James V.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661599/
https://www.ncbi.nlm.nih.gov/pubmed/19151202
http://dx.doi.org/10.2337/db08-1428