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Mice With Hyperghrelinemia Are Hyperphagic and Glucose Intolerant and Have Reduced Leptin Sensitivity
OBJECTIVE: Ghrelin is the only known peripheral hormone to increase ingestive behavior. However, its role in the physiological regulation of energy homeostasis is unclear because deletion of ghrelin or its receptor does not alter food intake or body weight in mice fed a normal chow diet. We hypothes...
Autores principales: | Bewick, Gavin A., Kent, Aysha, Campbell, Daniel, Patterson, Michael, Ghatei, Mohammed A., Bloom, Stephen R., Gardiner, James V. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661599/ https://www.ncbi.nlm.nih.gov/pubmed/19151202 http://dx.doi.org/10.2337/db08-1428 |
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